Key result
Levothyroxine therapy (150 mcg daily) reduced TSH levels from 31.42 to 14.17 μIU/mL in less than two weeks and managed moderate pericardial effusion in a 68-year-old male with hypothyroidism.
Case Report (n=1)
Uncontrolled hypothyroidism is a rare but reversible cause of moderate pericardial effusion that can be effectively managed with thyroid hormone replacement therapy.
Supports hypothyroidism as reversible pericardial effusion cause; single case leaves open need for prospective confirmation.
Hypothyroidism is an endocrine disorder with worldwide prevalence that can affect multiple organ systems. It can be asymptomatic and subclinical or overtly symptomatic with a potential to get complicated by fatal pathologies. It is an established cause of pericardial effusion, which in turn can be complicated by cardiac tamponade and severe hemodynamic instability. Herein we report the case of a 68-year-old male with history of Graves' disease treated with radioiodine ablation and consequent hypothyroidism, presenting with moderate pericardial effusion.
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Mirwais et al. (2019) conducted a case report in Hypothyroidism with pericardial effusion (n=1). Levothyroxine was evaluated on Reduction in TSH level and management of pericardial effusion. Levothyroxine therapy (150 mcg daily) reduced TSH levels from 31.42 to 14.17 μIU/mL in less than two weeks and managed moderate pericardial effusion in a 68-year-old male with hypothyroidism.
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