Key result
Slow-frequency rTMS improves post-stroke motor dexterity and reaction time compared to sham stimulation.
RCT
Sham-controlled
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Sham-controlled trial demonstrates low-frequency rTMS to the intact hemisphere enhances motor function in stroke patients, indicating reduced interhemispheric inhibition aids recovery.
The authors investigated the use of slow-frequency repetitive transcranial magnetic stimulation (rTMS) to the unaffected hemisphere to decrease interhemispheric inhibition of the lesioned hemisphere and improve motor function in patients within 12 months of a stroke. Patients showed a significant decrease in simple and choice reaction time and improved performance of the Purdue Pegboard test with their affected hand after rTMS of the motor cortex in the intact hemisphere as compared with sham rTMS.
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Mansur et al. (2005) conducted an RCT in Stroke. Slow-frequency repetitive transcranial magnetic stimulation (rTMS) to the unaffected hemisphere vs. Sham rTMS was evaluated on Simple and choice reaction time and performance of the Purdue Pegboard test with the affected hand. Slow-frequency rTMS of the unaffected hemisphere significantly decreased simple and choice reaction time and improved Purdue Pegboard performance vs sham in patients within 12 months of stroke.
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