Why the study?
Over the last 50 years, the epidemiology of HCM has changed with increased awareness and advanced diagnostic tools, prompting an evaluation of temporal trends in patient characteristics at diagnosis.
Population
7286 patients with HCM diagnosed at age ≥18 years
Comparison
Three eras of diagnosis: <2000 vs 2000–2010 vs >2010
Design
Retrospective multinational registry analysis
Authors
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Shifts in HCM presentation may refine screening thresholds; leaves open drivers and outcome implications.
The epidemiology of HCM has shifted over the past 40 years toward older age at diagnosis, milder phenotypes, and more sporadic, genotype-negative disease.
Canepa et al. (2020) studied this question.
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