Why the study?
Does the use of multiple arterial grafts improve outcomes compared to traditional single arterial and saphenous vein grafts in elderly patients undergoing CABG?
Does the use of multiple arterial grafts improve outcomes compared to traditional single arterial and saphenous vein grafts in elderly patients undergoing CABG?
Careful clinical judgment is necessary when selecting arterial grafts for elderly patients undergoing CABG, avoiding bilateral internal thoracic arteries in those at high risk for sternal complications.
Requires cautious conduit selection in elderly CABG patients; leaves open randomized confirmation of multiple arterial grafting benefits.
Although improved long-term outcomes obtained with the use of arterial grafts for coronary revascularization in comparison with the traditional association of a single arterial and saphenous vein grafts have been demonstrated in the overall population, the efficacy of this newer technique in the elderly is difficult to prove because their shorter life expectancy due to advanced heart disease, associated with severe comorbidities. Moreover, more widespread use of this technique is limited by the concerns on the potential morbidity, particularly the longer time required to perform the operation and the possibility of deep sternal wound infection in case of bilateral internal thoracic artery harvesting due to the decreased blood supply to the sternum and surrounding tissues.The review of the recent literature indicates that the use of bilateral internal thoracic arteries in very elderly patients should not be considered routinely. It seems reasonable to avoid it in octogenarians in the presence of well-known predictors of sternal complications such as diabetes, morbid obesity, and severe chronic lung disease.There is also still controversy about the superiority of the radial artery over the saphenous vein graft as a second or third conduit for surgical myocardial revascularization, although the majority of recent studies seem to support more liberal use of the radial artery as second arterial conduit in the elderly. Although a clinical benefit of arterial graft revascularization cannot be formally excluded for elderly patients, the increased complexity of this technique suggests that careful clinical judgment is necessary to select grafts for individual patients.
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Nicolini et al. (2017) studied this question.
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