Why the study?
Does the B2AR Gln27 homozygous genotype increase the risk of sudden cardiac death compared to Glu27 carriers?
Does the B2AR Gln27 homozygous genotype increase the risk of sudden cardiac death compared to Glu27 carriers?
The B2AR Gln27 homozygous genotype is associated with a significantly increased risk of sudden cardiac death, suggesting a genetic basis for SCD susceptibility.
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May flag B2AR Gln27 homozygosity as SCD risk marker; hypothesis-generating and requires prospective validation before clinical use.
Sotoodehnia et al. (2006) studied this question.
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