Why the study?
Do children with partial epilepsy have altered heart rate variability during sleep compared to normal controls?
Population
22 children, comprising 11 patients with partial epilepsy and 11 normal control subjects.
Design
Case-control
Authors
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Suggests autonomic imbalance during sleep in pediatric epilepsy; hypothesis-generating for SUDEP risk, needs prospective confirmation.
Do children with partial epilepsy have altered heart rate variability during sleep compared to normal controls?
Children with partial epilepsy demonstrate altered cardiac autonomic function during sleep, particularly during REM sleep, which may be relevant to the pathophysiology of sudden unexplained death in epilepsy (SUDEP).
Ferri et al. (2002) studied this question.
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