Why the study?
Does current use of SSRIs increase the risk of re-operation due to post-surgical bleeding in women undergoing primary breast cancer surgery?
Population
14,464 Danish women with primary breast cancer undergoing primary surgery
Comparison
Current use of selective serotonin reuptake… vs Never users of SSRI
Design
Cohort
Follow-up
14 days
Authors
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SSRI use was associated with higher re-operation risk after breast cancer surgery; hypothesis-generating and should not yet change perioperative practice.
Does current use of SSRIs increase the risk of re-operation due to post-surgical bleeding in women undergoing primary breast cancer surgery?
Current use of SSRIs is associated with a 2.3-fold increased relative risk of re-operation due to bleeding after breast cancer surgery, though the absolute risk remains low.
Gärtner et al. (2010) studied this question.
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