Human Pat1b Connects Deadenylation with mRNA Decapping and Controls the Assembly of Processing Bodies

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Pat1 Contains Distinct Functional Domains That Promote P-Body Assembly and Activation of Decapping2007 · 122 citations
2. 2HPat provides a link between deadenylation and decapping in metazoa2010 · 80 citations
3. 3Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure.1993 · 378 citations
4. 4TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements2007 · 246 citations
5. 5The decapping activator Lsm1p-7p–Pat1p complex has the intrinsic ability to distinguish between oligoadenylated and polyadenylated RNAs2007 · 169 citations