Why the study?
Does dofetilide improve termination of atrial flutter compared to quinidine in a canine model?
Does dofetilide improve termination of atrial flutter compared to quinidine in a canine model?
Dofetilide is more effective than quinidine in terminating experimental atrial flutter, correlating with its ability to prolong wavelength and reduce dispersion of refractoriness.
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May favor dofetilide in experimental atrial flutter; hypothesis-generating and should not change practice.
Cha et al. (1996) studied this question.
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