Why the study?
Do baseline levels of NT-proBNP, CRP, and creatinine clearance predict subsequent cardiovascular events in patients with stable coronary heart disease?
Population
1051 patients aged 30 to 70 years with stable coronary heart disease (CHD)
Comparison
Measurement of baseline serum N-terminal… vs Lower levels of the respective biomarkers
Design
Cohort
Follow-up
mean of 48.7 months
Authors
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NT-proBNP may refine risk stratification in stable CHD; extends prior observational data but leaves open whether it guides therapy or improves outcomes.
Do baseline levels of NT-proBNP, CRP, and creatinine clearance predict subsequent cardiovascular events in patients with stable coronary heart disease?
NT-proBNP is a strong, independent predictor of recurrent cardiovascular events in patients with stable coronary heart disease, providing complementary prognostic information to established risk factors.
Dietrich Rothenbacher (2006) studied this question.
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