Why the study?
Does a high-osmolarity lot of sodium antimony gluconate cause severe cardiotoxicity in kala-azar patients?
Does a high-osmolarity lot of sodium antimony gluconate cause severe cardiotoxicity in kala-azar patients?
A high-osmolarity lot of sodium antimony gluconate was associated with life-threatening cardiotoxicity, including heart failure and fatal arrhythmias, highlighting the need for osmolarity monitoring.
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High-osmolarity sodium antimony gluconate was associated with fatal cardiotoxicity; leaves open whether osmolarity monitoring prevents harm in kala-azar.
Sundar et al. (1998) studied this question.
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