July 29, 2015BMC Research NotesOpen Access

Efficacy of weekly docetaxel in locally advanced cardiac angiosarcoma

View Full Paper

Ask AI

Bookmark

Population

1 Caucasian 23-year-old man with locally advanced cardiac angiosarcoma.

Design

Case_report

Follow-up

2 years

Authors

SMSantino MinichilloAzienda USL di Bologna MPMaria A. PantaleoUniversity of Pisa MNMargherita NanniniAzienda USL di Bologna

Discussion

Member takes

Implication

May support non-anthracycline regimens as a bridge to resection in cardiac angiosarcoma; leaves open need for prospective validation.

Structured PICO

Population

1 Caucasian 23-year-old man with locally advanced cardiac angiosarcoma (8.4 cm mass in right atrium with mediastinal adenopathies and pulmonary micronodules).

Intervention

Neoadjuvant weekly docetaxel (35 mg/mq) for 4 cycles, followed by concurrent radiotherapy (5,400 cGy) and continued docetaxel up to 24 cycles, followed by radical surgical resection and 10 cycles of adjuvant docetaxel.

Outcome

Tumor response allowing for surgical resection and overall survival

Weekly docetaxel combined with radiotherapy may enable radical surgical resection in locally advanced cardiac angiosarcoma while avoiding anthracycline-induced cardiotoxicity.

Cite This Study

Minichillo et al. (2015) studied this question.

synapsesocial.com/papers/6a7cfe098fc303b9e22faaa9 https://doi.org/10.1186/s13104-015-1296-4

View Full Paper

Ask AI

Bookmark

Efficacy of weekly docetaxel in locally advanced cardiac angiosarcoma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Efficacy of weekly docetaxel in locally advanced cardiac angiosarcoma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider