Racial Differences in the Incidence of Chronic Kidney Disease
Why the study?
Does African American race increase the incidence of chronic kidney disease compared to white race in young adults?
Population
4,119 young adults, 18-30 years of age, with an estimated GFR ≥60 ml/min per 1.73 m² at baseline from the…
Comparison
African American race (exposure) vs White race
Design
Cohort
Follow-up
20 years
Authors
Discussion
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Member takes
Implication
Albuminuria adjustment attenuates racial disparity in young-adult CKD incidence; hypothesis-generating for targeted prevention trials.
Structured PICO
Does African American race increase the incidence of chronic kidney disease compared to white race in young adults?
P
Population
4,119 young adults, 18-30 years of age, with an estimated GFR (eGFR) ≥60 ml/min per 1.73 m² at baseline from the community-based Coronary Artery Risk Development in Young Adults (CARDIA) study.
I
Intervention
African American race (exposure)
C
Comparator
White race
O
Outcome
Incident CKD (defined as an eGFR <60 ml/min per 1.73 m² and a ≥25% decline in eGFR at study visits conducted 10, 15, and 20 years after baseline)surrogate
African Americans have a significantly higher 20-year incidence of CKD compared to whites, a disparity that is largely explained by differences in albuminuria.
Cite This Study
Muntner et al. (2011) studied this question.