Why the study?
Telmisartan is an angiotensin receptor blocker used alone or with other blood pressure-lowering medications for hypertension, prompting a review of synthetic methodologies for its preparation.
This review provides an overview of the chemical synthesis methods for the antihypertensive drug telmisartan.
Provides overview of telmisartan syntheses; leaves open validation of scalable or greener routes.
A chronic illness that is prevalent throughout the globe, hypertension is a major probability factor for cardiovascular disease. An angiotensin receptor blocker may be a better initial antihypertensive medication for patients who are resistant to angiotensin-converting enzyme inhibiting agents, such as telmisartan. Telmisartan can be used either alone or in conjunction with other medications that lower blood pressure. This review covers the various synthetic methodologies used for the preparation of telmisartan and their characterization for structural elucidation.
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Shaik et al. (2025) studied this question.
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