The tautomerism of 4,4/5,5‐disubstituted 4 H /5 H ‐imidazol‐5/4‐ones has been investigated by ir, uv, and p K studies. In nonpolar solvents the non‐conjugated tautomer predominates, but in polar solvents varying amounts of the conjugated tautomer may also be observed. The proportion of conjugated tautomer is increased by the presence of electron‐releasing groups at the 2‐position.
No takes yet. Share an insight, caveat, or question.
Edward et al. (1972) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: