Assessing the outcomes of implantable cardioverter defibrillator treatment in a real world setting: results from hospital record data
View Full Paper
Ask AI
Bookmark
Share
Why the study?
Does implantable cardioverter defibrillator treatment reduce mortality in a real-world hospital population?
Population
169,488 patients from the hospital discharge database of the Friuli Venezia Giulia region in Italy. The…
Comparison
Implantable cardioverter defibrillator… vs Matched controls without ICD
Design
Cohort
Follow-up
2 to 10 years
Authors
Discussion
Loading...
Member takes
Implication
Supports real-world ICD mortality benefit; leaves open net value given higher rehospitalization and costs.
Structured PICO
Does implantable cardioverter defibrillator treatment reduce mortality in a real-world hospital population?
P
Population
169,488 patients (334,764 admissions) from the hospital discharge database of the Friuli Venezia Giulia region in Italy (1997-2007). The matched subsample included 905 ICD patients and 5,962 controls. Mean age of ICD patients was approximately 66 years, with ~16% female. Most common primary diagnoses for ICD patients were primary cardiomyopathy (41%) and paroxysmal ventricular tachycardia (23%).
I
Intervention
Implantable cardioverter defibrillator (ICD) implantation
C
Comparator
Matched controls without ICD (exact matching on age class, gender, year of admission, type of admission, primary diagnosis, and Charlson Comorbidities Index)
O
Outcome
Mortality at 1, 2, and 3 yearshard clinical
In a real-world setting, ICD implantation was associated with significantly reduced mortality but higher re-hospitalization rates and healthcare expenditures compared to matched controls.
Limitations
- Potential unobserved confounding factors influencing the decision to implant an ICD
- Reliance on administrative data and DRG tariffs as a proxy for hospital costs
Cite This Study
Ghislandi et al. (2013) studied this question.
Topics
View Full Paper
Ask AI
Bookmark
Share