Gelatin-Based Films with a Multifunctional Three-Component Deep Eutectic System as a Potential Biomaterial

High Resolution Image Download MS PowerPoint Slide Gelatin (GL), widely used in material applications, is limited by its inherent brittleness and low antioxidant activity. To address these shortcomings, we present a study of GL-based films modified with an innovative three-component deep eutectic solvent (DES) composed of choline chloride, tannic acid, and citric acid. This modification aimed to enhance the mechanical, antioxidant, and UV-protective properties of the GL films. ATR-FTIR spectroscopy confirmed the molecular interactions between GL and DES components. The incorporation of DES improved the films’ flexibility, with elongation at break reaching up to 252%, while maintaining structural integrity. Additionally, the films exhibited outstanding antioxidant activity, with DPPH scavenging values reaching 94%, significantly surpassing the activity of unmodified GL. Importantly, cytotoxicity testing using L929 fibroblasts confirmed acceptable biocompatibility of the materials. The films also demonstrated exceptional UV shielding, effectively covering the UV spectrum while retaining high transparency in the visible range. These findings highlight the potential of DES-modified GL films as versatile materials for applications requiring enhanced mechanical flexibility, antioxidant performance, and UV protection, particularly in the field of bioplastics.