Integrated study of 100 patients with Xp21 linked muscular dystrophy using clinical, genetic, immunochemical, and histopathological data. Part 1. Trends across the clinical groups.

100 patients with Xp21 linked muscular dystrophy (Duchenne and Becker dystrophy), ages 4 to 66 years, examined in Newcastle, who had undergone a muscle biopsy and provided a blood sample for DNA analysis.

Trends in gene and protein expression across clinical groups, correlation of gene and protein expression, and assessment of relative usefulness of different techniques in diagnosis and prognosis.surrogate