January 12, 1988Acta Medica Scandinavica

Long‐term Efficacy of Flecainide in Paroxysmal Atrial Fibrillation

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Why the study?

Does flecainide prevent attacks in patients with frequent paroxysmal atrial fibrillation refractory to previous antiarrhythmic drugs?

Population

20 patients with very frequent attacks of paroxysmal atrial fibrillation for many years, previously…

Design

Case_series, open trial

Follow-up

6 months

Authors

CSC. SonnhagLinköping University AKAnders KallrydSkaraborg Hospital ENEva NylanderLinköping University

Discussion

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Implication

May support flecainide in refractory paroxysmal AF; leaves open confirmation in randomized trials.

Structured PICO

Does flecainide prevent attacks in patients with frequent paroxysmal atrial fibrillation refractory to previous antiarrhythmic drugs?

Population

20 patients with very frequent attacks (mean 13 per month) of paroxysmal atrial fibrillation for many years (mean 8 years), previously unsuccessfully treated with an average of 3.3 antiarrhythmic drugs.

Intervention

Flecainide

Outcome

Efficacy (freedom from AF attacks) judged from a daily diary over a 6-month follow-up periodpatient reported

Flecainide is highly effective for long-term prevention of paroxysmal atrial fibrillation in patients refractory to multiple other antiarrhythmic drugs.

Cite This Study

Sonnhag et al. (1988) studied this question.

synapsesocial.com/papers/6a7d09aab0b0e582d537cc7b https://doi.org/10.1111/j.0954-6820.1988.tb19627.x

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF AF ablation outcomes

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Long‐term Efficacy of Flecainide in Paroxysmal Atrial Fibrillation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Long‐term Efficacy of Flecainide in Paroxysmal Atrial Fibrillation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider