Why the study?
The comorbidity of chronic obstructive pulmonary disease and cardiovascular diseases is a relevant healthcare problem due to their high prevalence, continued growth, and shared risk factors and pathophysiological mechanisms.
This review highlights the shared risk factors and pathophysiological mechanisms between COPD and cardiovascular diseases, emphasizing the clinical implications for diagnosis and treatment.
Shared COPD-CVD pathways warrant integrated screening; leaves open prospective trials on combined therapies.
Currently, the comorbidity (combination) of chronic obstructive pulmonary disease (COPD) and cardiovascular diseases (CVD) is an relevant problem for health care. This is due to the high prevalence and continued growth of these pathologies. CVD and COPD have common risk factors and mechanisms underlying their development and progression: smoking, inflammation, sedentary lifestyle, aging, oxidative stress, air pollution, and hypoxia. In this review, we summarize current knowledge relating to the prevalence and frequency of cardiovascular diseases in people with COPD and the mechanisms that underlie their coexistence. The implications for clinical practice, in particular the main problems of diagnosis and treatment of COPD/CVD comorbidity, are also discussed.
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Aleksey M. Chaulin (2020) studied this question.
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