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This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the comparative effectiveness and safety of immunotherapy (anti PD‐1, anti PD‐L1, or anti CTLA‐4) plus chemotherapy compared to chemotherapy alone for the first‐line systemic treatment of extensive‐stage small cell lung cancer with a network meta‐analysis, and to identify relevant biomarkers or clinical factors.
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Ichimura et al. (2024) studied this question.
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