Why the study?
What is the incidence of major bleeding with oral anticoagulant therapy in patients with non-rheumatic atrial fibrillation in routine clinical practice?
Population
433 patients with non-rheumatic atrial fibrillation starting treatment and routinely followed at Italian…
Design
Cohort
Follow-up
mean 1.4 years
Authors
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Age >75 years associated with higher OAC bleeding risk in AF warrants caution; leaves open optimal strategies in routine practice.
What is the incidence of major bleeding with oral anticoagulant therapy in patients with non-rheumatic atrial fibrillation in routine clinical practice?
In routine clinical practice, oral anticoagulation for non-rheumatic atrial fibrillation is effective but carries a significantly higher risk of major bleeding in patients over 75 years of age.
Legnani et al. (2001) studied this question.
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