Why the study?
Does amiloride 10 mg improve outcomes compared to spironolactone 25 mg in patients with hypertension resistant to a multidrug regime including an angiotensin-blocking agent?
Does amiloride 10 mg improve outcomes compared to spironolactone 25 mg in patients with hypertension resistant to a multidrug regime including an angiotensin-blocking agent?
Amiloride 10 mg is less effective than spironolactone 25 mg for resistant hypertension.
Amiloride may be less effective than spironolactone in resistant hypertension; hypothesis-generating and should not yet change practice.
University Department of Medicine, City Hospital, Birmingham, UK Correspondence to Dr Deirdre A. Lane, University Department of Medicine, City Hospital, Birmingham, UK Tel: +44 0121 507 5080; fax: +44 0121 507 5914; e-mail: [email protected]
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Lane et al. (2007) studied this question.
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