January 1, 2004Journal of Pharmacological SciencesOpen Access

Forefront of Na+/Ca2+ Exchanger Studies: Molecular Pharmacology of Na+/Ca2+ Exchange Inhibitors

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TITakahiro IwamotoOkayama University

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Implication

Should not yet change cardiovascular practice; hypothesis-generating for NCX-targeted therapies in ischemic disease, arrhythmias, and heart failure.

Structured PICO

Intervention

Na+/Ca2+ exchange inhibitors (KB-R7943, SEA0400, and SN-6)

Benzyloxyphenyl derivatives are selective NCX inhibitors with defined molecular binding sites, offering potential therapeutic avenues for ischemic disease, arrhythmias, and heart failure.

Cite This Study

Takahiro Iwamoto (2004) studied this question.

synapsesocial.com/papers/6a7d16440ae9e6500d83d501 https://doi.org/10.1254/jphs.fmj04002x6

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Implication

Should not yet change cardiovascular practice; hypothesis-generating for NCX-targeted therapies in ischemic disease, arrhythmias, and heart failure.

Forefront of Na+/Ca2+ Exchanger Studies: Molecular Pharmacology of Na+/Ca2+ Exchange Inhibitors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Forefront of Na+/Ca2+ Exchanger Studies: Molecular Pharmacology of Na+/Ca2+ Exchange Inhibitors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider