Why the study?
Purulent pericardial effusions are rare and represent the most severe form of bacterial pericarditis, with invasive non-typhoid Salmonella cardiac infection being a rare but important consideration in immunocompromised individuals.
Highlights invasive non-typhoid Salmonella as a rare cause of purulent pericarditis and cardiac tamponade, particularly relevant in immunocompromised populations such as those with HIV.
Alerts clinicians to non-typhoid Salmonella pericarditis in immunocompromised patients in sub-Saharan Africa; hypothesis-generating for targeted diagnostics.
Purulent pericardial effusions are rare and represent the most severe form of bacterial pericarditis. The authors present a case of a male in his 40s with a massive purulent pericardial effusion due to non-typhoid Salmonella, who presented with ultrasound features of a cardiac tamponade. Invasive non-typhoid Salmonella cardiac infection is a rare but important consideration in immunocompromised individuals. This of particular concern in sub-Saharan Africa, where there is a high prevalence of HIV-infected individuals.
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Jacobs et al. (2022) studied this question.
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