November 15, 1993Annals of Internal Medicine
Smoking Cessation in Relation to Total Mortality Rates in Women: A Prospective Cohort Study
Why the study?
Does smoking cessation reduce total mortality in middle-aged women?
Population
117,001 female registered nurses, ages 30 to 55 years, residing in the United States, free of manifest…
Comparison
Smoking cessation (former smokers) vs Continuing smokers and never smokers
Design
Cohort
Follow-up
12 years
Authors
Discussion
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Member takes
Implication
Smoking cessation was associated with lower mortality risk in middle-aged women; leaves open whether benefits are causal without randomized confirmation.
Structured PICO
Does smoking cessation reduce total mortality in middle-aged women?
P
Population
117,001 female registered nurses, ages 30 to 55 years, residing in the United States, free of manifest coronary heart disease, stroke, and cancer (except nonmelanoma skin cancer) at baseline.
I
Intervention
Smoking cessation (former smokers)
C
Comparator
Continuing smokers (current smokers) and never smokers
O
Outcome
Total mortalityhard clinical
Smoking cessation significantly reduces total and cardiovascular mortality in middle-aged women, with risks approaching those of never smokers after 10 to 14 years of abstinence.
Cite This Study
Ichiro Kawachi (1993) studied this question.