Why the study?
Does increasing K+ concentration inhibit adrenergic neurotransmission in isolated dog saphenous veins?
Does increasing K+ concentration inhibit adrenergic neurotransmission in isolated dog saphenous veins?
Potassium ions cause relaxation of venous smooth muscle constricted by sympathetic stimulation by inhibiting the release of norepinephrine from nerve endings.
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Suggests ionic modulation of sympathetic venous tone in animals; leaves open relevance to human hyperkalemia or vascular control.
Lorenz et al. (1975) studied this question.
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