Why the study?
Does major bleeding increase the risk of mortality and morbidity in patients with acute coronary syndromes?
Population
133,597 patients with acute coronary syndromes (ACS) pooled from 10 retrospective or prospective studies
Comparison
Major bleeding (exposure) vs No major bleeding
Design
Meta-analysis
Follow-up
in-hospital or 30-day
Authors
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Major bleeding strongly predicts short-term mortality in ACS; confirms bleeding prevention as a key target for practice and trials.
Does major bleeding increase the risk of mortality and morbidity in patients with acute coronary syndromes?
Major bleeding in patients with acute coronary syndromes is a strong predictor of short-term mortality and myocardial infarction, emphasizing the need for bleeding prevention strategies.
Hamon et al. (2007) studied this question.
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