Why the study?
What is the natural clinical course of muscular subaortic stenosis and how does symptomatic improvement compare between propranolol therapy and ventriculomyotomy?
Population
60 patients with hemodynamically proved muscular subaortic stenosis
Comparison
Propranolol therapy or ventriculomyotomy vs Untreated or comparison between medical and…
Design
Cohort
Follow-up
Average 10 years from murmur to symptoms, and 5 years from…
Authors
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May support ventriculomyotomy over propranolol for severe symptoms; leaves open need for randomized confirmation of progression and differential benefit.
What is the natural clinical course of muscular subaortic stenosis and how does symptomatic improvement compare between propranolol therapy and ventriculomyotomy?
Muscular subaortic stenosis is a progressive disease where surgical ventriculomyotomy provides more sustained symptomatic relief for severe symptoms compared to propranolol therapy.
Allan G. Adelman (1972) studied this question.
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