Arrhythmogenic right ventricular cardiomyopathy: diagnosis, prognosis, and treatment
Why the study?
Does methenamine hippurate prevent UTI in adult women with recurrent UTIs?
Population
6 RCTs involving 557 adult women (aged ≥18 years) in the community with a history of recurrent UTIs
Comparison
Methenamine hippurate prophylactically vs Placebo, no treatment, or antibiotics
Design
Systematic_review
Follow-up
6 or 12 months
Authors
Discussion
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Member takes
Implication
Insufficient evidence precludes recommending methenamine hippurate over antibiotics for recurrent UTI; larger trials needed to confirm benefit.
Structured PICO
Does methenamine hippurate prevent UTI in adult women with recurrent UTIs?
P
Population
6 RCTs involving 557 adult women (aged ≥18 years) in the community with a history of recurrent UTIs
I
Intervention
Methenamine hippurate prophylactically
C
Comparator
Placebo, no treatment, or antibiotics
O
Outcome
Number of patients who remained asymptomatic
There is currently insufficient evidence to confirm the benefits of methenamine hippurate for preventing recurrent UTIs in adult women.
Limitations
- Antibiotic use and resistance were not consistently reported
Cite This Study
Domenico Corrado (2000) studied this question.