What question did this study set out to answer?

To compare mortality outcomes between hemodialysis and peritoneal dialysis in elderly patients with end-stage renal disease.

May 4, 2015Clinical Journal of the American Society of Nephrology

Dialysis Modality and Mortality in the Elderly

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Authors

SHSeung Seok HanSeoul National University SKSoohee KangSeoul National University Hospital KKKyoung Hoon KimSeoul National University

Discussion

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Implication

Cohort study and meta-analysis reveals higher mortality with peritoneal dialysis versus hemodialysis in elderly patients, suggesting hemodialysis confers superior survival.

Key Points

To compare mortality outcomes between hemodialysis and peritoneal dialysis in elderly patients with end-stage renal disease.
Analyzed 13,065 incident elderly dialysis patients (age ≥65 years; hemodialysis n=10,675, peritoneal dialysis n=2390) from the Korean Health Insurance dataset over a mean follow-up of 1.8±1.3 years (maximum 5 years) using multivariate Cox models.
Conducted a meta-analysis pooling the Korean cohort with 15 population-based studies published since 2000, encompassing >631,421 elderly patients.
In the Korean cohort, peritoneal dialysis was associated with a higher mortality rate compared with hemodialysis (HR 1.20, 95% CI 1.13 to 1.28; P<0.001).
In the pooled meta-analysis of >631,421 patients across 15 studies, peritoneal dialysis was associated with higher mortality than hemodialysis (pooled HR 1.10, 95% CI 1.01 to 1.20).
Survival advantages of hemodialysis were significantly amplified among elderly patients with diabetes mellitus, dialysis duration exceeding 1 year, and cohorts initiating dialysis during the 1990s.

Cite This Study

Han et al. (2015) studied this question.

synapsesocial.com/papers/6a7d1fe400c5c9efbcaa0c24 https://doi.org/10.2215/cjn.05160514

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May 4, 2015Clinical Journal of the American Society of Nephrology

Dialysis Modality and Mortality in the Elderly

View Full Paper

Ask AI

Bookmark

Authors

SHSeung Seok HanSeoul National University SKSoohee KangSeoul National University Hospital KKKyoung Hoon KimSeoul National University

Discussion

Member takes

Implication

Cohort study and meta-analysis reveals higher mortality with peritoneal dialysis versus hemodialysis in elderly patients, suggesting hemodialysis confers superior survival.

Key Points

To compare mortality outcomes between hemodialysis and peritoneal dialysis in elderly patients with end-stage renal disease.
Analyzed 13,065 incident elderly dialysis patients (age ≥65 years; hemodialysis n=10,675, peritoneal dialysis n=2390) from the Korean Health Insurance dataset over a mean follow-up of 1.8±1.3 years (maximum 5 years) using multivariate Cox models.
Conducted a meta-analysis pooling the Korean cohort with 15 population-based studies published since 2000, encompassing >631,421 elderly patients.
In the Korean cohort, peritoneal dialysis was associated with a higher mortality rate compared with hemodialysis (HR 1.20, 95% CI 1.13 to 1.28; P<0.001).
In the pooled meta-analysis of >631,421 patients across 15 studies, peritoneal dialysis was associated with higher mortality than hemodialysis (pooled HR 1.10, 95% CI 1.01 to 1.20).
Survival advantages of hemodialysis were significantly amplified among elderly patients with diabetes mellitus, dialysis duration exceeding 1 year, and cohorts initiating dialysis during the 1990s.

Cite This Study

Han et al. (2015) studied this question.

synapsesocial.com/papers/6a7d1fe400c5c9efbcaa0c24 https://doi.org/10.2215/cjn.05160514

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