The Marfanoid Hypermobility Syndrome

A patient had the marfanoid habitus but no evidence of evolvement of the aorta or dislocation of the lenses. This was associated with extreme, generalized hypermobility of the joints and marked hyperextensibility of the skin, suggesting the Ehlers-Danlos syndrome. There have been at least four previous reports of this combination of findings. The clinical features of this condition differ significantly from those of both the Marfan syndrome and the Ehlers-Danlos syndrome, and it is suggested that this marfanoid hypermobility syndrome is a distinct entity within the heritable disorders of connective tissue.