December 2, 2010Medical Decision Making
Predicting EQ-5D Utility Scores from the Seattle Angina Questionnaire in Coronary Artery Disease
Why the study?
Can Seattle Angina Questionnaire (SAQ) scores be accurately mapped to EQ-5D utility scores in patients with coronary artery disease?
Population
1992 patients with coronary artery disease from the Alberta Provincial Project for Outcome Assessment in…
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports SAQ-to-EQ-5D mapping for mean utility estimates in CAD economic analyses; leaves open external validation across broader cohorts.
Structured PICO
Can Seattle Angina Questionnaire (SAQ) scores be accurately mapped to EQ-5D utility scores in patients with coronary artery disease?
P
Population
1992 patients with coronary artery disease from the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) database
I
Intervention
Mapping algorithms (simple linear regression and Tobit models) to translate Seattle Angina Questionnaire (SAQ) scores into EQ-5D utility scores
O
Outcome
Model performance assessed by comparing predicted and observed mean EQ-5D scores in the validation set, and the unadjusted R2patient reported
Mean EQ-5D utility weights can be accurately estimated from the SAQ using a simple linear regression mapping algorithm, enabling economic evaluations in CAD studies.
Cite This Study
Wijeysundera et al. (2010) studied this question.