What question did this study set out to answer?

To evaluate clinician prescribing behavior and antibiotic discontinuation rates after receiving respiratory panel or procalcitonin results indicative of a viral respiratory infection.

September 1, 2015Infectious Diseases and TherapyOpen Access

Antibiotic Discontinuation Rates Associated with Positive Respiratory Viral Panel and Low Procalcitonin Results in Proven or Suspected Respiratory Infections

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Authors

TTTristan T. TimbrookBarnes-Jewish Hospital MMMeshell MaxamJackson Memorial Hospital JBJohn A. BossoMedical University of South Carolina

Discussion

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Implication

Retrospective analysis reveals infrequent antibiotic discontinuation following viral respiratory panel and low procalcitonin results, indicating a need for active stewardship interventions.

Key Points

To evaluate clinician prescribing behavior and antibiotic discontinuation rates after receiving respiratory panel or procalcitonin results indicative of a viral respiratory infection.
Retrospective single-center analysis of hospitalized patients with documented proven or suspected acute respiratory infections.
Included 2,031 patients who had a respiratory panel (RP) or procalcitonin (PCT) test obtained within 72 hours of hospital presentation.
Evaluated antibiotic discontinuation rates within 48 hours following a PCT <0.25 μg/mL, a positive viral RP, or both.
Of 2,031 included patients, 789 were potential candidates for antibiotic avoidance (219 with PCT <0.25 μg/mL, 601 with a positive viral RP, and 31 with both).
Antibiotics were initiated within the first 72 hours in 307 of the 789 candidate patients (39%).
Positive viral testing and low procalcitonin concentrations were infrequently associated with prompt antibiotic cessation in clinical practice.

Cite This Study

Timbrook et al. (2015) studied this question.

synapsesocial.com/papers/6a7d244e149bd8e2c5749449 https://doi.org/10.1007/s40121-015-0087-5

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Implication

Retrospective analysis reveals infrequent antibiotic discontinuation following viral respiratory panel and low procalcitonin results, indicating a need for active stewardship interventions.

Antibiotic Discontinuation Rates Associated with Positive Respiratory Viral Panel and Low Procalcitonin Results in Proven or Suspected Respiratory Infections

Discussion

Member takes

Implication

Key Points

Cite This Study

Antibiotic Discontinuation Rates Associated with Positive Respiratory Viral Panel and Low Procalcitonin Results in Proven or Suspected Respiratory Infections

Discussion

Member takes

Implication

Key Points

Cite This Study

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