What question did this study set out to answer?

To evaluate the comparative effectiveness of different mammography-based screening strategies across age groups, screening intervals, and modalities on breast cancer morbidity and mortality.

April 30, 2024JAMA

Screening for Breast Cancer

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Authors

WNWanda K. NicholsonMilken Institute MSMichael SilversteinTufts University JWJohn B. WongTufts University

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Implication

Systematic review reveals moderate net benefit of biennial mammography in women aged 40 to 74 years, indicating routine screening should start at age 40.

Key Points

To evaluate the comparative effectiveness of different mammography-based screening strategies across age groups, screening intervals, and modalities on breast cancer morbidity and mortality.
Conducted a systematic evidence review and collaborative modeling studies to assess comparative breast cancer screening strategies.
Evaluated cisgender women and all other persons assigned female at birth aged 40 years or older at average risk of breast cancer.
Biennial screening mammography in women aged 40 to 74 years demonstrates a moderate net benefit in reducing breast cancer mortality (USPSTF B recommendation).
Evidence is insufficient to determine the balance of benefits and harms of screening mammography in women aged 75 years or older (USPSTF I statement).
Evidence is insufficient to assess the balance of benefits and harms of supplemental screening with breast ultrasound or MRI in women with dense breasts on a negative mammogram (USPSTF I statement).

Cite This Study

Nicholson et al. (2024) studied this question.

synapsesocial.com/papers/6a7d24908253d2b4939ffdc5 https://doi.org/10.1001/jama.2024.5534

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Implication

Systematic review reveals moderate net benefit of biennial mammography in women aged 40 to 74 years, indicating routine screening should start at age 40.

Screening for Breast Cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

Screening for Breast Cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

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