What question did this study set out to answer?

To document the clinical course and radiological healing of an acute descending aortic dissection managed non-operatively with targeted blood pressure control.

July 1, 1987HeartOpen Access

Spontaneous resolution of a dissection of the descending aorta after medical treatment with a beta blocker and a calcium antagonist.

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Why the study?

Does medical treatment with metoprolol and nicardipine lead to spontaneous resolution of acute descending aortic dissection?

Population

A 58-year-old man with acute dissection of the descending aorta

Design

Case_report

Follow-up

266 days

Authors

THT HoshinoHamamatsu University School of Medicine MOMinoru OhmaeKochi Rehabilitation Institute ASA Sakai

Discussion

Member takes

Implication

May support medical therapy in acute descending aortic dissection; single case leaves open reproducibility and generalizability.

Key Points

To document the clinical course and radiological healing of an acute descending aortic dissection managed non-operatively with targeted blood pressure control.
Administered metoprolol and nicardipine to a 58-year-old male with acute descending aortic dissection to sustain blood pressure below 130/90 mm Hg.
Tracked structural vascular changes using serial contrast-enhanced computed tomography scans through 266 days of follow-up.
Serial imaging demonstrated opacification of the initially unopacified false lumen by day 42 and moderate regression by day 67.
Complete resolution of the aortic false lumen occurred by day 266 without surgical intervention.

Structured PICO

Does medical treatment with metoprolol and nicardipine lead to spontaneous resolution of acute descending aortic dissection?

Population

A 58-year-old man with acute dissection of the descending aorta

Intervention

Medical treatment with metoprolol and nicardipine to maintain blood pressure below 130/90 mm Hg

Outcome

Resolution of the false lumen detected by serial contrast-enhanced computed tomographic scanssurrogate

This case provides the first in vivo demonstration of spontaneous resolution of an acute descending aortic dissection following medical therapy with a beta-blocker and calcium antagonist.

Cite This Study

Hoshino et al. (1987) studied this question.

synapsesocial.com/papers/6a7d2597e9ddcd9870aa0f89 https://doi.org/10.1136/hrt.58.1.82

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Spontaneous resolution of a dissection of the descending aorta after medical treatment with a beta blocker and a calcium antagonist.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Spontaneous resolution of a dissection of the descending aorta after medical treatment with a beta blocker and a calcium antagonist.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Also Consider