Why the study?
Is periodontal disease associated with endothelial dysfunction measured by flow-mediated dilation in a general population?
Population
1,234 subjects aged 25-85 years from the 5-year follow-up of the Study of Health in Pomerania, a…
Comparison
High levels of periodontal disease, assessed by… vs Subjects with lower levels or absence of…
Design
Cross-sectional
Authors
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Severe periodontitis associated with higher FMD; challenges prior reports but remains hypothesis-generating in cross-sectional data.
Is periodontal disease associated with endothelial dysfunction measured by flow-mediated dilation in a general population?
In contrast to previous studies, severe periodontal disease was significantly associated with higher flow-mediated dilation values, and this association was not mediated by systemic inflammation.
Holtfreter et al. (2013) studied this question.
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