Late recurrence of osteosarcoma can be successfully managed with complete resection and chemotherapy, leading to prolonged disease-free survival.
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May support resection and chemotherapy for late osteosarcoma recurrence; hypothesis-generating from Level 5 evidence only.
We report 2 cases of late recurrence of osteosarcoma after 6 and 7 years. One patient had pulmonary metastasis, and the other had soft tissue recurrence. Both patients underwent complete resection and chemotherapy. The first patient achieved complete remission and remained disease-free 47 months later and had no limitation in his daily life. The second patient had a re-recurrence and underwent further resection and chemotherapy. He remained disease-free 35 months later and could walk using a T-handled walking cane.
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Igarashi et al. (2014) studied this question.
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