Key result
Repeated pulmonary resections for metastatic osteogenic sarcoma resulted in prolonged survival, with the patient alive and tumor-free 14 years after initial ablative surgery.
Why the study?
Can repeated pulmonary resections improve long-term survival in patients with metastatic osteogenic sarcoma?
Case Report (n=1)
Can repeated pulmonary resections improve long-term survival in patients with metastatic osteogenic sarcoma?
Repeated pulmonary resections for metastatic osteosarcoma can result in prolonged long-term survival.
Answers are grounded in this paper and cite their sources.
May support repeated resections for survival in select metastatic osteogenic sarcoma cases; hypothesis-generating and requires prospective validation.
This case report discusses the clinical course of a gentleman who is alive today without evidence of tumor 14 years following above knee amputation for osteogenic sarcoma of the distal femur. Twice during the two years following his initial ablative surgery, metastatic pulmonary foci were identified and resected. The latter procedure required partial chest wall and pneumonectomy resection.Survival beyond ten years occasionally occurs following initial ablative surgery for osteogenic sarcoma. Prolonged survival has only rarely been reported following repeated pulmonary resection procedures. The extent of his second resection procedure is noteworthy, in light of the early evidence of recurrent or residual disease a few months after initial thoracotomy.The potential for long-term survival exists in a substantial fraction of patients with osteosarcoma metastatic to the lung.
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Light et al. (1981) conducted a case report in Metastatic osteogenic sarcoma (n=1). Repeated pulmonary resections was evaluated on Survival without evidence of tumor. Repeated pulmonary resections for metastatic osteogenic sarcoma resulted in prolonged survival, with the patient alive and tumor-free 14 years after initial ablative surgery.
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