Key result
Aggressive pulmonary resections for osteogenic sarcoma metastases yielded a 31% 5-year survival rate compared to 2% in untreated controls.
Why the study?
Does aggressive pulmonary resection improve 5-year survival in patients with osteogenic sarcoma and pulmonary metastasis?
Population
167 patients with osteogenic sarcoma and pulmonary metastasis, including 22 patients under age 21 subjected…
Comparison
Aggressive pulmonary resections combined with… vs No pulmonary resection.
Design
Cohort
Follow-up
5 years
Authors
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May support resection in selected patients with resectable metastases; leaves open need for randomized confirmation.
Cohort (n=167)
Does aggressive pulmonary resection improve 5-year survival in patients with osteogenic sarcoma and pulmonary metastasis?
Absolute Event Rate: 31% vs 2%
Aggressive pulmonary resection combined with chemotherapy may significantly improve 5-year survival in patients with osteogenic sarcoma and pulmonary metastases.
Marcove et al. (1975) conducted a cohort in Osteogenic sarcoma with pulmonary metastasis (n=167). Aggressive pulmonary resections vs. Untreated pulmonary metastases was evaluated on 5-year survival. Aggressive pulmonary resections for osteogenic sarcoma metastases yielded a 31% 5-year survival rate compared to 2% in untreated controls.
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