Key result
Surgical resection of lung metastases in osteosarcoma patients yielded a 37% 5-year survival among those rendered disease-free, whereas chemotherapy offered little advantage for bulk disease.
Why the study?
Does surgical resection or chemotherapy improve survival and disease response in patients with osteosarcoma and pulmonary metastases?
Population
44 patients with osteosarcoma and pulmonary metastases treated between 1977 and 1985 at Institut Curie and…
Design
Cohort
Follow-up
5 years
Authors
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May support metastasectomy in selected osteosarcoma patients; hypothesis-generating and should not yet change practice.
Cohort (n=44)
Yes
Does surgical resection or chemotherapy improve survival and disease response in patients with osteosarcoma and pulmonary metastases?
Surgical resection of lung metastases appears to improve outcomes in osteosarcoma patients, whereas chemotherapy offers little advantage for bulk disease.
Belli et al. (1989) conducted a cohort in Osteosarcoma with pulmonary metastases (n=44). Surgical resection of lung metastases vs. Chemotherapy for measurable lung disease was evaluated on 5-year survival. Surgical resection of lung metastases in osteosarcoma patients yielded a 37% 5-year survival among those rendered disease-free, whereas chemotherapy offered little advantage for bulk disease.
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