Synthesis of γ-Iodo-allylic Diboronic Esters via Atom Transfer Radical Addition of (Diborylmethyl)iodide to Alkynes

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Herein, we disclose a manganese-catalyzed approach that enables the direct iododiborylcarbofunctionalization of alkynes with a (diboronmethyl)iodide under mild conditions. This approach grants access to a range of structurally unique and synthetically useful γ-iodine-substituted gem -bis(boronate)s, which have hitherto been inaccessible. This atom-economical strategy displays excellent functional-group tolerance, encompasses a wide range of applicable substrates, and demonstrates a high Z: E selectivity (up to 96:4).