Answers are grounded in this paper and cite their sources.
The Pd-catalyzed reaction between β-iodo-β-silylstyrenes and terminal alkynes in i-Pr2NEt gave 1,2,3,5-tetrasubstituted benzenes with complete regioselection. The use of certain silylacetylenes as alkynes enabled efficient synthesis of 1,3,5-trissilyl-2-arylbenzenes, which could be transformed into other multisubstituted benzenes by displacement of the silyl groups.
No takes yet. Share an insight, caveat, or question.
Kinoshita et al. (2013) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: