Mortality of Neurofibromatosis in Japan, 1968–1992

The death rate from neurofibromatosis (NF) was analyzed using Japanese vital statistics for the period 1968-1992. NF death rates for females decreased significantly year by year, but there was no significant change for males. Overall NF death rates were 0.25 per million population for males and 0.19 for females. The age-specific NF death rate increased with age during that period. The overall mean age at death from NF was 43 years for both sexes. There were no geographical variations in the NF death rate during the period 1977-1992.