A breakthrough in the asymmetric hydroboration of notoriously difficult 1,1-disubstituted alkenes using a new family of highly effective hydroboration reagents is described (see scheme). The intermediate boranes can be oxidized to alcohols or used in Suzuki-Miyaura cross-coupling reactions.
No takes yet. Share an insight, caveat, or question.
Thomas et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: