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May 1, 1982Journal of Biological ChemistryOpen Access

4-Bromocrotonic acid, an effective inhibitor of fatty acid oxidation and ketone body degradation in rat heart mitochondria. On the rate-determining step of beta-oxidation and ketone body degradation in heart.

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YOY OloweNewYork–Presbyterian HospitalHSHorst SchulzHelmholtz Centre for Environmental Research

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Olowe et al. (1982) studied this question.

synapsesocial.com/papers/6a7d3a6a3575152c8237d83ahttps://doi.org/10.1016/s0021-9258(19)83791-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inhibition of fatty acid oxidation by 2-bromooctanoate. Evidence for the enzymatic formation of 2-bromo-3-ketooctanoyl coenzyme A and the inhibition of 3-ketothiolase.1979 · 58 citations
  2. 2Specificity of carnitine action on fatty acid oxidation by heart muscle1962 · 108 citations
  3. 3PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT1951 · 318,692 citations
  4. 4The Reaction of Fumarase with Iodoacetate and 4-Bromocrotonate1969 · 46 citations
  5. 5d-β-Hydroxybutyric Dehydrogenase of Mitochondria1960 · 296 citations