Severe Neutropenia Associated with Fluoxetine Hydrochloride

Letters1 October 1997Severe Neutropenia Associated with Fluoxetine HydrochlorideFelix D. Vilinsky, MD and Alan Lubin, MDFelix D. Vilinsky, MDMt. Sinai Medical Center; Cleveland, OH 44106 and Alan Lubin, MDMt. Sinai Medical Center; Cleveland, OH 44106Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-7-199710010-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:A 79-year-old man, wheelchair-bound because of residual right hemiparesis from remote stroke, presented with increased fatigue, weakness, and recent history of febrile illness that had resolved spontaneously. Results of physical examination were normal except for neurologic findings related to the stroke. Medications included fluoxetine hydrochloride (Prozac, Dista Products, Indianapolis, Indiana), warfarin, glipizide, diphenhydramine, and tobramycin-dexamethasone ophthalmic drops.Hemogram showed a leukocyte count of 2800 cells/mm3 with granulocytopenia and significant monocytosis (0% segmented cells, 11% band cells, 2% metamyelocytes, 45% lymphocytes, 36% monocytes, and 6% eosinophils). Hemoglobin level (16.2 g/dL), platelet count (277 000 cells/mm3), and mean corpuscular ... Author, Article, and Disclosure InformationAuthors: Felix D. Vilinsky, MD; Alan Lubin, MDAffiliations: Mt. Sinai Medical Center; Cleveland, OH 44106 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLow-dose and repeated exposure to fluoxetine leads to eryptosis and hematological disorder in Wistar ratsSertraline-Induced Neutropenia and Fatigue in a Patient With End-Stage Renal DiseaseFluoxetineParoxetineAripiprazole-Associated Leukopenia With Coadministration of FluoxetineANTIDEPRESSANTSLeukopenia Associated with Paroxetine UseFluoxetineMonoaminergic‐based Pharmacotherapy for DepressionSafety and side effect profile of fluoxetineNeutropenia Associated with Mirtazapine Use: Is a Drop in the Neutrophil Count in a symptomatic Older Adults a Cause for Concern?Mirtazapine and bone marrow suppression: A case reportAntidepressant drugsAplastic anaemia during treatment with fluoxetineFluoxetine 1 October 1997Volume 127, Issue 7Page: 573-574KeywordsAntibodiesCellsDrug therapyLymphocytesMean corpuscular volumeMonocytesNeutropeniaNeutrophilsPlateletsStroke ePublished: 15 August 2000 Issue Published: 1 October 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...