Why the study?
Does mindfulness-based stress reduction (MBSR) or cognitive-behavioral therapy (CBT) reduce oxidative stress and interleukin 6 in patients with primary hypertension?
Does mindfulness-based stress reduction (MBSR) or cognitive-behavioral therapy (CBT) reduce oxidative stress and interleukin 6 in patients with primary hypertension?
Mindfulness-based stress reduction and cognitive-behavioral therapy may be effective in reducing inflammatory and oxidative stress markers in patients with primary hypertension.
Cardiovascular diseases are the leading cause of death in developing countries. Research has shown that the level of oxidative stress and interleukin 6 (IL-6) is higher in individuals with hypertension than individuals with normal blood pressure. Therefore, the aim of the present randomized clinical trial study was to compare the effectiveness of mindfulness-based stress reduction (MBSR) and cognitive-behavioral therapy (CBT) on oxidative stress and interleukin 6. Sixty patients with primary hypertension were divided into two intervention groups (MBSR and CBT) and one control group. Oxidative stress and IL-6 were measured by prooxidant-antioxidant balance (PAB) and ELISA method (Biovendor kit), respectively. Data analysis was carried out using ANOVA and MANCOVA in SPSS Ver.19. The results showed that MBSR significantly reduced oxidative stress. Also, MBSR and CBT significantly reduced IL-6 levels.
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Birashk et al. (2018) studied this question.
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