August 1, 1975Acta Physiologica Scandinavica

Vasomotor Nerve Control of Isolated Arteries and Veins

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Population

Isolated blood vessel preparations: rabbit proximal/distal saphenous and ear arteries, parietal branch of…

Comparison

Transmural nerve stimulation vs Exogenous noradrenaline (NA)

Design

Preclinical

Authors

BLBengt LjungAstraZeneca (United Kingdom)JBJohn A. BevanUniversity of Vermont BPBarbara L. PegramUniversity of California, Los Angeles

Discussion

Member takes

Implication

Animal data on venous-arterial neurogenic differences should not guide therapy; leaves open translation to human sympathetic control mechanisms.

Structured PICO

Population

Isolated blood vessel preparations: rabbit proximal/distal saphenous and ear arteries, parietal branch of internal iliac vein, small saphenous vein, pulmonary artery strips; and rat portal vein longitudinal preparations.

Intervention

Transmural nerve stimulation (low ≤4 Hz and high ≥8 Hz frequencies)

Comparator

Exogenous noradrenaline (NA)

Outcome

Frequency-response relationships (steady state responses expressed as a percentage of maximum response to exogenous NA)surrogate

Veins exhibit steeper frequency-response relationships to transmural nerve stimulation compared to arteries, suggesting differences in neurogenic vascular control mechanisms.

Cite This Study

Ljung et al. (1975) studied this question.

synapsesocial.com/papers/6a7d4022d3686d25b46e52ba https://doi.org/10.1111/j.1748-1716.1975.tb05910.x

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Implication

Animal data on venous-arterial neurogenic differences should not guide therapy; leaves open translation to human sympathetic control mechanisms.

Vasomotor Nerve Control of Isolated Arteries and Veins

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Vasomotor Nerve Control of Isolated Arteries and Veins

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider