Why the study?
The study aimed to establish an acute canine coronary artery occlusion model by implanting a mixed thrombus prepared in vitro into the coronary artery using percutaneous coronary intervention.
A canine model of acute coronary occlusion can be successfully established using minimally invasive PCI to implant an in vitro-prepared mixed thrombus.
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New canine PCI occlusion model may aid preclinical testing; leaves open clinical translation pending validation.
Ma et al. (2023) studied this question.
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